Carcinoma–associated fibroblasts (CAF) are a heterogeneous group of cells within the tumor microenvironment (TME) that can promote tumorigenesis in the prostate. By understanding the mechanism(s) by which CAF contributes to tumor growth, new …
A hierarchical reciprocal graphical models to infer gene networks from heterogeneous data with or without known groups.
A Gaussian reciprocal graphical model for inference about gene regulatory relationships by integrating mRNA gene expression and DNA level information including copy number and methylation.
A review of directed, undirected, and reciprocal graphs.
An array-variate directed acyclic graphical model for tensor data.
This is a discussion on using sparse random network models as prior distributions in graphical models.
Bayesian methods have found many successful applications in high-throughput genomics. We focus on approaches for network-based inference from gene expression data. Methods that employ sparse priors have been particularly successful, as they are …
A Bayesian directed acyclic graphical model to recover the structure of nonlinear gene regulatory networks.
An integrative Bayesian network approach to investigate the relationships between genetic and epigenetic alterations as well as how these mutations affect a patient’s clinical outcome.